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Control of catalytic efficiency by a coevolving network of catalytic and noncatalytic residues
The active sites of enzymes consist of residues necessary for catalysis and structurally important noncatalytic residues that together maintain the architecture and function of the active site. Examples of evolutionary interactions between catalytic and noncatalytic residues have been difficult to d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060692/ https://ncbi.nlm.nih.gov/pubmed/24912189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322352111 |
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