Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture

Microglia, the immunocompetent cells of the CNS, are rapidly activated in response to injury and microglia migration towards and homing at damaged tissue plays a key role in CNS regeneration. Lysophosphatidic acid (LPA) is involved in signaling events evoking microglia responses through cognate G pr...

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Détails bibliographiques
Auteurs principaux: Bernhart, Eva, Kollroser, Manfred, Rechberger, Gerald, Reicher, Helga, Heinemann, Akos, Schratl, Petra, Hallström, Seth, Wintersperger, Andrea, Nusshold, Christoph, DeVaney, Trevor, Zorn-Pauly, Klaus, Malli, Roland, Graier, Wolfgang, Malle, Ernst, Sattler, Wolfgang
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060044/
https://ncbi.nlm.nih.gov/pubmed/19899077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200900195
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