Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture

Microglia, the immunocompetent cells of the CNS, are rapidly activated in response to injury and microglia migration towards and homing at damaged tissue plays a key role in CNS regeneration. Lysophosphatidic acid (LPA) is involved in signaling events evoking microglia responses through cognate G pr...

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Detalhes bibliográficos
Main Authors: Bernhart, Eva, Kollroser, Manfred, Rechberger, Gerald, Reicher, Helga, Heinemann, Akos, Schratl, Petra, Hallström, Seth, Wintersperger, Andrea, Nusshold, Christoph, DeVaney, Trevor, Zorn-Pauly, Klaus, Malli, Roland, Graier, Wolfgang, Malle, Ernst, Sattler, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060044/
https://ncbi.nlm.nih.gov/pubmed/19899077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200900195
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