GABA(A) Receptor Antagonism Ameliorates Behavioral and Synaptic Impairments Associated with MeCP2 Overexpression

Methyl-CpG-binding protein 2 (MeCP2) is a ubiquitously expressed transcriptional regulator with functional importance in the central nervous system. Loss-of-function mutations in MECP2 results in the neurodevelopmental disorder, Rett syndrome, whereas increased expression levels are associated with...

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Main Authors: Na, Elisa S, Morris, Michael J, Nelson, Erika D, Monteggia, Lisa M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059904/
https://ncbi.nlm.nih.gov/pubmed/24549116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.43
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