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The dynamics of SecM-induced translational stalling
SecM is an E. coli secretion monitor capable of stalling translation on the prokaryotic ribosome without co-factors. Biochemical and structural studies have demonstrated that the SecM nascent chain interacts with the 50S subunit exit tunnel to inhibit peptide bond formation. However, the timescales...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059775/ https://ncbi.nlm.nih.gov/pubmed/24836001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.033 |
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