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Dynamic pathways of -1 translational frameshifting

Spontaneous changes in the reading frame of translation are rare (frequency of 10(−3) – 10(−4) per codon)(1), but can be induced by specific features in the messenger RNA (mRNA). In the presence of mRNA secondary structures, a heptanucleotide “slippery sequence” usually defined by the motif X XXY YY...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Chen, Jin, Petrov, Alexey, Johansson, Magnus, Tsai, Albert, O’Leary, Seán E., Puglisi, Joseph D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472451/
https://ncbi.nlm.nih.gov/pubmed/24919156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13428
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