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Dynamic pathways of -1 translational frameshifting
Spontaneous changes in the reading frame of translation are rare (frequency of 10(−3) – 10(−4) per codon)(1), but can be induced by specific features in the messenger RNA (mRNA). In the presence of mRNA secondary structures, a heptanucleotide “slippery sequence” usually defined by the motif X XXY YY...
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| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472451/ https://ncbi.nlm.nih.gov/pubmed/24919156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13428 |
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