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Coordinated conformational and compositional dynamics drive ribosome translocation

During translation elongation, the compositional factors, elongation factor G (EF-G; encoded by fusA) and transfer RNA (tRNA), alternately bind to the ribosome to direct protein synthesis, in turn regulating the conformation of the ribosome. Here, we use single-molecule fluorescence with zero-mode w...

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Detalhes bibliográficos
Main Authors: Chen, Jin, Petrov, Alexey, Tsai, Albert, O’Leary, Seán E., Puglisi, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883222/
https://ncbi.nlm.nih.gov/pubmed/23624862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2567
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