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Non-fluorescent Quenchers to Correlate Single-Molecule Conformational and Compositional Dynamics

Single-molecule Förster resonance energy transfer (smFRET) is a powerful method to study the conformational dynamics of a biomolecule in real-time. However, studying how interacting ligands correlate with and regulate the conformational dynamics of the biomolecule is extremely challenging due to the...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Chen, Jin, Tsai, Albert, Petrov, Alexey, Puglisi, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369913/
https://ncbi.nlm.nih.gov/pubmed/22428667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2119964
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