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The dynamics of SecM-induced translational stalling
SecM is an E. coli secretion monitor capable of stalling translation on the prokaryotic ribosome without co-factors. Biochemical and structural studies have demonstrated that the SecM nascent chain interacts with the 50S subunit exit tunnel to inhibit peptide bond formation. However, the timescales...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059775/ https://ncbi.nlm.nih.gov/pubmed/24836001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.033 |
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