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Transgenic mice expressing S129 phosphorylation mutations in α-synuclein

Aggregated α-synuclein is a predominant constituent of Lewy bodies, the intracellular protein aggregates seen in Parkinson’s disease. While most α-synuclein in the nervous system is unphosphorylated, the majority of α-synuclein in Lewy bodies is phosphorylated at serine 129 (S129). We developed tran...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Escobar, Valerie Drews, Kuo, Yien-Ming, Orrison, Bonnie M., Giasson, Benoit I., Nussbaum, Robert L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059511/
https://ncbi.nlm.nih.gov/pubmed/24486885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.01.033
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