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Translational inhibition of α-synuclein by Posiphen normalizes distal colon motility in transgenic Parkinson mice

Parkinson disease (PD) is a neurodegenerative disease with motor as well as non-motor symptoms, including gastrointestinal dysfunction. In humans, these precede the motor symptoms by decades. Previously developed and characterized transgenic mice expressing the mutant human α-synuclein gene (SNCA) (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Neurodegener Dis
Prif Awduron: Kuo, Yien-Ming, Nwankwo, Ejike Innocent, Nussbaum, Robert L, Rogers, Jack, Maccecchini, Maria L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420700/
https://ncbi.nlm.nih.gov/pubmed/30906671
Tagiau: Ychwanegu Tag
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