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Translational inhibition of α-synuclein by Posiphen normalizes distal colon motility in transgenic Parkinson mice

Parkinson disease (PD) is a neurodegenerative disease with motor as well as non-motor symptoms, including gastrointestinal dysfunction. In humans, these precede the motor symptoms by decades. Previously developed and characterized transgenic mice expressing the mutant human α-synuclein gene (SNCA) (...

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Detalhes bibliográficos
Publicado no:Am J Neurodegener Dis
Main Authors: Kuo, Yien-Ming, Nwankwo, Ejike Innocent, Nussbaum, Robert L, Rogers, Jack, Maccecchini, Maria L
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420700/
https://ncbi.nlm.nih.gov/pubmed/30906671
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