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The alpha-synuclein 5(′)untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen
Increased brain α-synuclein (SNCA) protein expression resulting from gene duplication and triplication can cause a familial form of Parkinson’s disease (PD). Dopaminergic neurons exhibit elevated iron levels that can accelerate toxic SNCA fibril formation. Examinations of human post mortem brain hav...
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| Publicat a: | J Neural Transm (Vienna) |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6625511/ https://ncbi.nlm.nih.gov/pubmed/21221670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-010-0513-5 |
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