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Augmentation of phenotype in a transgenic Parkinson mouse heterozygous for a Gaucher mutation

The involvement of the protein α-synuclein (SNCA) in the pathogenesis of Parkinson’s disease is strongly supported by the facts that (i) missense and copy number mutations in the SNCA gene can cause inherited Parkinson’s disease; and (ii) Lewy bodies in sporadic Parkinson’s disease are largely compo...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Fishbein, Ianai, Kuo, Yien-Ming, Giasson, Benoit I., Nussbaum, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240298/
https://ncbi.nlm.nih.gov/pubmed/25351739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu291
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