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Transgenic mice expressing S129 phosphorylation mutations in α-synuclein
Aggregated α-synuclein is a predominant constituent of Lewy bodies, the intracellular protein aggregates seen in Parkinson’s disease. While most α-synuclein in the nervous system is unphosphorylated, the majority of α-synuclein in Lewy bodies is phosphorylated at serine 129 (S129). We developed tran...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059511/ https://ncbi.nlm.nih.gov/pubmed/24486885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.01.033 |
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