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Enhancing the Efficiency and Regioselectivity of P450 Oxidation Catalysts via Unnatural Amino Acid Mutagenesis
The development of effective strategies for modulating the reactivity and selectivity of cytochrome P450 enzymes represents a key step toward expediting the use of these biocatalysts for synthetic applications. In this work, we investigated the potential of unnatural amino acid mutagenesis to aid ef...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059402/ https://ncbi.nlm.nih.gov/pubmed/24692265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201400060 |
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