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A General Method for Scanning Unnatural Amino Acid Mutagenesis

Current approaches to protein site-directed mutagenesis require an independent user operation for each mutation. This can impede large-scale scanning mutagenesis projects such as mapping protein interaction surfaces, active sites, or epitopes. It also prevents the creation of protein libraries of de...

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Détails bibliographiques
Auteurs principaux: Daggett, Kelly A., Layer, Mark, Cropp, T. Ashton
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765485/
https://ncbi.nlm.nih.gov/pubmed/19199564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800271f
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