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Using Unnatural Amino Acid Mutagenesis to Probe the Regulation of PRMT1()
Protein arginine methyltransferase 1 (PRMT1)-dependent methylation contributes to the onset and progression of numerous diseases (e.g., cancer, heart disease, ALS), however, the regulatory mechanisms that control PRMT1 activity are relatively unexplored. We therefore set out to decipher how phosphor...
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| Publicado en: | ACS Chem Biol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505744/ https://ncbi.nlm.nih.gov/pubmed/24358983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400859z |
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