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Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations

The utilization of unnatural amino acids (UAAs) in bioconjugations is ideal due to their ability to confer a degree of bioorthogonality and specificity. In order to elucidate optimal conditions for the preparation of bioconjugates with UAAs, we synthesized 9 UAAs with variable methylene tethers (2–4...

詳細記述

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書誌詳細
出版年:Bioconjug Chem
主要な著者: Maza, Johnathan C., McKenna, Jaclyn R., Raliski, Benjamin K., Freedman, Matthew T., Young, Douglas D.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455997/
https://ncbi.nlm.nih.gov/pubmed/26287719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00424
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