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Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations

The utilization of unnatural amino acids (UAAs) in bioconjugations is ideal due to their ability to confer a degree of bioorthogonality and specificity. In order to elucidate optimal conditions for the preparation of bioconjugates with UAAs, we synthesized 9 UAAs with variable methylene tethers (2–4...

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Bibliografiset tiedot
Julkaisussa:Bioconjug Chem
Päätekijät: Maza, Johnathan C., McKenna, Jaclyn R., Raliski, Benjamin K., Freedman, Matthew T., Young, Douglas D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455997/
https://ncbi.nlm.nih.gov/pubmed/26287719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00424
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