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Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations
The utilization of unnatural amino acids (UAAs) in bioconjugations is ideal due to their ability to confer a degree of bioorthogonality and specificity. In order to elucidate optimal conditions for the preparation of bioconjugates with UAAs, we synthesized 9 UAAs with variable methylene tethers (2–4...
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| Veröffentlicht in: | Bioconjug Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5455997/ https://ncbi.nlm.nih.gov/pubmed/26287719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00424 |
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