Probing the role of loop 2 in Ras function with unnatural amino acids.

The YDPT sequence motif (residues 32-35) in loop 2 (residues 32-40) of Ha-Ras p21 protein is conserved in the Ras protein family. X-ray crystal structures have revealed significant conformational differences in this region between the GTP- and GDP-bound forms. Moreover, mutations in this region bloc...

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Bibliografiske detaljer
Main Authors: Chung, H H, Benson, D R, Cornish, V W, Schultz, P G
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47730/
https://ncbi.nlm.nih.gov/pubmed/8234268
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