Probing the role of loop 2 in Ras function with unnatural amino acids.

The YDPT sequence motif (residues 32-35) in loop 2 (residues 32-40) of Ha-Ras p21 protein is conserved in the Ras protein family. X-ray crystal structures have revealed significant conformational differences in this region between the GTP- and GDP-bound forms. Moreover, mutations in this region bloc...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chung, H H, Benson, D R, Cornish, V W, Schultz, P G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10145
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