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Synthesis and coupling reactions of alpha,alpha-dialkylated amino acids with nucleobase side chains.

Several di- and tripeptides containing protected purine (adenine) and pyrimidine (thymine) residues on their side chains were synthesized. The parent amino acids alpha, alpha-dialkylated in a symmetrical manner. An effective coupling procedure was developed for these sterically hindered amino acids:...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Azumaya, I, Aebi, R, Kubik, S, Rebek, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618834/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12013
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