RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

The neuronal microtubule-associated protein Tau is expressed in different variants, and changes in Tau isoform composition occur during development and disease. Here, we investigate a potential role of the multivalent tau mRNA-binding proteins G3BP1 and IMP1 in regulating neuronal tau expression. We...

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Bibliografiska uppgifter
Huvudupphovsmän: Moschner, Katharina, Sündermann, Frederik, Meyer, Heiko, da Graca, Abel Pereira, Appel, Neele, Paululat, Achim, Bakota, Lidia, Brandt, Roland
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059124/
https://ncbi.nlm.nih.gov/pubmed/24755223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541425
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