Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides

[Image: see text] The anticancer drug bexarotene has been shown to restore cognitive functions in animal models of Alzheimer’s disease, but its exact mechanism of action remains elusive. In the present report, we have used a combination of molecular, physicochemical, and cellular approaches to eluci...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Fantini, Jacques, Di Scala, Coralie, Yahi, Nouara, Troadec, Jean-Denis, Sadelli, Kevin, Chahinian, Henri, Garmy, Nicolas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058752/
https://ncbi.nlm.nih.gov/pubmed/24383913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400183w
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky