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Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?

After three decades of false hopes and failures, a pipeline of therapeutic drugs that target the actual root cause of Alzheimer's disease (AD) is now available. Challenging the old paradigm that focused on β‐amyloid peptide (Aβ) aggregation in amyloid plaques, these compounds are designed to pr...

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Библиографические подробности
Опубликовано в: :Protein Sci
Главные авторы: Fantini, Jacques, Chahinian, Henri, Yahi, Nouara
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380673/
https://ncbi.nlm.nih.gov/pubmed/32567070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3906
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