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Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?

After three decades of false hopes and failures, a pipeline of therapeutic drugs that target the actual root cause of Alzheimer's disease (AD) is now available. Challenging the old paradigm that focused on β‐amyloid peptide (Aβ) aggregation in amyloid plaques, these compounds are designed to pr...

詳細記述

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書誌詳細
出版年:Protein Sci
主要な著者: Fantini, Jacques, Chahinian, Henri, Yahi, Nouara
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380673/
https://ncbi.nlm.nih.gov/pubmed/32567070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3906
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