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Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?

After three decades of false hopes and failures, a pipeline of therapeutic drugs that target the actual root cause of Alzheimer's disease (AD) is now available. Challenging the old paradigm that focused on β‐amyloid peptide (Aβ) aggregation in amyloid plaques, these compounds are designed to pr...

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Publicat a:Protein Sci
Autors principals: Fantini, Jacques, Chahinian, Henri, Yahi, Nouara
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380673/
https://ncbi.nlm.nih.gov/pubmed/32567070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3906
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