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Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?

After three decades of false hopes and failures, a pipeline of therapeutic drugs that target the actual root cause of Alzheimer's disease (AD) is now available. Challenging the old paradigm that focused on β‐amyloid peptide (Aβ) aggregation in amyloid plaques, these compounds are designed to pr...

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Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Fantini, Jacques, Chahinian, Henri, Yahi, Nouara
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380673/
https://ncbi.nlm.nih.gov/pubmed/32567070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3906
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