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Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?

After three decades of false hopes and failures, a pipeline of therapeutic drugs that target the actual root cause of Alzheimer's disease (AD) is now available. Challenging the old paradigm that focused on β‐amyloid peptide (Aβ) aggregation in amyloid plaques, these compounds are designed to pr...

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書目詳細資料
發表在:Protein Sci
Main Authors: Fantini, Jacques, Chahinian, Henri, Yahi, Nouara
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Inc. 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380673/
https://ncbi.nlm.nih.gov/pubmed/32567070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3906
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