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Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides
[Image: see text] The anticancer drug bexarotene has been shown to restore cognitive functions in animal models of Alzheimer’s disease, but its exact mechanism of action remains elusive. In the present report, we have used a combination of molecular, physicochemical, and cellular approaches to eluci...
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| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2014
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058752/ https://ncbi.nlm.nih.gov/pubmed/24383913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400183w |
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