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Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection

The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral repl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Antimicrob Agents
Prif Awduron: Fantini, Jacques, Di Scala, Coralie, Chahinian, Henri, Yahi, Nouara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier B.V. and International Society of Chemotherapy. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128678/
https://ncbi.nlm.nih.gov/pubmed/32251731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2020.105960
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