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Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection

The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral repl...

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Bibliographic Details
Published in:Int J Antimicrob Agents
Main Authors: Fantini, Jacques, Di Scala, Coralie, Chahinian, Henri, Yahi, Nouara
Format: Artigo
Language:Inglês
Published: Elsevier B.V. and International Society of Chemotherapy. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128678/
https://ncbi.nlm.nih.gov/pubmed/32251731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2020.105960
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