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Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides

[Image: see text] The anticancer drug bexarotene has been shown to restore cognitive functions in animal models of Alzheimer’s disease, but its exact mechanism of action remains elusive. In the present report, we have used a combination of molecular, physicochemical, and cellular approaches to eluci...

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Bibliografiset tiedot
Päätekijät: Fantini, Jacques, Di Scala, Coralie, Yahi, Nouara, Troadec, Jean-Denis, Sadelli, Kevin, Chahinian, Henri, Garmy, Nicolas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058752/
https://ncbi.nlm.nih.gov/pubmed/24383913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400183w
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