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Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides
[Image: see text] The anticancer drug bexarotene has been shown to restore cognitive functions in animal models of Alzheimer’s disease, but its exact mechanism of action remains elusive. In the present report, we have used a combination of molecular, physicochemical, and cellular approaches to eluci...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058752/ https://ncbi.nlm.nih.gov/pubmed/24383913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400183w |
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