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Stat3 binds to mitochondrial DNA and regulates mitochondrial gene expression in keratinocytes

The nuclear transcription factor Stat3 has recently been reported to have a localized mitochondrial regulatory function. Current data suggest that mitochondrial Stat3 (mitoStat3) is necessary for maximal mitochondrial activity and for Ras-mediated transformation independent of Stat3 nuclear activity...

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Autors principals: Macias, Everardo, Rao, Dharanija, Carbajal, Steve, Kiguchi, Kaoru, DiGiovanni, John
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057971/
https://ncbi.nlm.nih.gov/pubmed/24496235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.68
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