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Stat3 binds to mitochondrial DNA and regulates mitochondrial gene expression in keratinocytes
The nuclear transcription factor Stat3 has recently been reported to have a localized mitochondrial regulatory function. Current data suggest that mitochondrial Stat3 (mitoStat3) is necessary for maximal mitochondrial activity and for Ras-mediated transformation independent of Stat3 nuclear activity...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057971/ https://ncbi.nlm.nih.gov/pubmed/24496235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.68 |
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