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Targeted disruption of Bcl-x(L) in mouse keratinocytes inhibits both UVB- and chemically-induced skin carcinogenesis

Bcl-x(L) is one of several antiapoptotic proteins regulated by signal transducer and activator of transcription 3 (Stat3). We have recently shown that Stat3 is required for chemically-induced and ultraviolet B (UVB)-induced skin carcinogenesis. In this study, the functional role of Bcl-x(L) in skin...

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Autori principali: Kim, Dae Joon, Kataoka, Ken, Sano, Shigetoshi, Connolly, Kevin, Kiguchi, Kaoru, DiGiovanni, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066197/
https://ncbi.nlm.nih.gov/pubmed/19309000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20527
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