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Dual inhibition of both the EGFR and erbB2 effectively inhibits promotion of skin tumors during two-stage carcinogenesis

The erbB family of receptor tyrosine kinases are known to play important roles in both normal epithelial development and epithelial neoplasia. Considerable evidence also suggests that signaling through the EGFR plays an important role in multistage skin carcinogenesis in mice; however, less is known...

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Detalhes bibliográficos
Main Authors: Kiguchi, Kaoru, Kitamura, Takuya, Moore, Tricia, Rumi, Mohammad, Chang, Hsiang-Chun, Treece, Devon, Ruffino, Lynnsie, Connolly, Kevin, DiGiovanni, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940063/
https://ncbi.nlm.nih.gov/pubmed/20682802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0010
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