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Dual inhibition of both the EGFR and erbB2 effectively inhibits promotion of skin tumors during two-stage carcinogenesis
The erbB family of receptor tyrosine kinases are known to play important roles in both normal epithelial development and epithelial neoplasia. Considerable evidence also suggests that signaling through the EGFR plays an important role in multistage skin carcinogenesis in mice; however, less is known...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940063/ https://ncbi.nlm.nih.gov/pubmed/20682802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0010 |
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