Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis

BACKGROUND: Osteogenesis is a highly regulated developmental process and continues during the turnover and repair of mature bone. Runx2, the master regulator of osteoblastogenesis, directs a transcriptional program essential for bone formation through genetic and epigenetic mechanisms. While individ...

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Autors principals: Wu, Hai, Whitfield, Troy W, Gordon, Jonathan A R, Dobson, Jason R, Tai, Phillip W L, van Wijnen, Andre J, Stein, Janet L, Stein, Gary S, Lian, Jane B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056528/
https://ncbi.nlm.nih.gov/pubmed/24655370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-3-r52
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