Molecular Switches Involving Homeodomain Proteins, HOXA10 and RUNX2 Regulate Osteoblastogenesis

The osteoinductive BMP2 signal facilitates commitment to the osteoblast phenotype by inducing several classes of early response genes. Among these are bone-related HOX factors, homeodomain, RUNX and OSTERIX proteins. Here we demonstrate molecular events among BMP2-induced transcription factors that...

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Detalhes bibliográficos
Main Authors: Hassan, Mohammad Q., Saini, Sharanjot, Gordon, Jonathan A.R., van Wijnen, Andre J., Montecino, Martin, Stein, Janet L., Stein, Gary S., Lian, Jane B.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
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Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665705/
https://ncbi.nlm.nih.gov/pubmed/18701816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151453
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