Pbx1 Represses Osteoblastogenesis by Blocking Hoxa10-Mediated Recruitment of Chromatin Remodeling Factors

Abdominal-class homeodomain-containing (Hox) factors form multimeric complexes with TALE-class homeodomain proteins (Pbx, Meis) to regulate tissue morphogenesis and skeletal development. Here we have established that Pbx1 negatively regulates Hoxa10-mediated gene transcription in mesenchymal cells a...

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Auteurs principaux: Gordon, Jonathan A. R., Hassan, Mohammad Q., Saini, Sharanjot, Montecino, Martin, van Wijnen, Andre J., Stein, Gary S., Stein, Janet L., Lian, Jane B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897555/
https://ncbi.nlm.nih.gov/pubmed/20439491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00889-09
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