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HOXA10 Controls Osteoblastogenesis by Directly Activating Bone Regulatory and Phenotypic Genes

HOXA10 is necessary for embryonic patterning of skeletal elements, but its function in bone formation beyond this early developmental stage is unknown. Here we show that HOXA10 contributes to osteogenic lineage determination through activation of Runx2 and directly regulates osteoblastic phenotypic...

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Hlavní autoři: Hassan, Mohammad Q., Tare, Rahul, Lee, Suk Hee, Mandeville, Matthew, Weiner, Brian, Montecino, Martin, van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899966/
https://ncbi.nlm.nih.gov/pubmed/17325044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01544-06
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