Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation

The ability to discover regulatory sequences that control bone-related genes during development has been greatly improved by massively parallel sequencing methodologies. To expand our understanding of cis-regulatory regions critical to the control of gene expression during osteoblastogenesis, we pro...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Tai, Phillip W. L., Wu, Hai, van Wijnen, André J., Stein, Gary S., Stein, Janet L., Lian, Jane B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703546/
https://ncbi.nlm.nih.gov/pubmed/29176792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188056
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