Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.
Long CTG triplet repeats which are associated with several human hereditary neuromuscular disease genes are stabilized in ColE1-derived plasmids in Escherichia coli containing mutations in the methyl-directed mismatch repair genes (mutS, mutL, or mutH). When plasmids containing (CTG)180 were grown f...
محفوظ في:
| الحاوية / القاعدة: | Proc Natl Acad Sci U S A |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
National Academy of Sciences
1995
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.11019 |
| الوسوم: |
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|