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Structural analysis of slipped-strand DNA (S-DNA) formed in (CTG)n. (CAG)n repeats from the myotonic dystrophy locus.

The mechanism of disease-associated trinucleotide repeat length variation may involve slippage of the triplet-containing strand at the replication fork, generating a slipped-strand DNA structure. We recently reported formation in vitro of slipped-strand DNA (S-DNA) structures when DNAs containing tr...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Pearson, C E, Wang, Y H, Griffith, J D, Sinden, R R
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1998
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147324/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.816
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