Structural analysis of slipped-strand DNA (S-DNA) formed in (CTG)n. (CAG)n repeats from the myotonic dystrophy locus.

The mechanism of disease-associated trinucleotide repeat length variation may involve slippage of the triplet-containing strand at the replication fork, generating a slipped-strand DNA structure. We recently reported formation in vitro of slipped-strand DNA (S-DNA) structures when DNAs containing tr...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Pearson, C E, Wang, Y H, Griffith, J D, Sinden, R R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9443975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.3.816
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!