Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.

Long CTG triplet repeats which are associated with several human hereditary neuromuscular disease genes are stabilized in ColE1-derived plasmids in Escherichia coli containing mutations in the methyl-directed mismatch repair genes (mutS, mutL, or mutH). When plasmids containing (CTG)180 were grown f...

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Bibliografiska uppgifter
Huvudupphovsmän: Jaworski, A, Rosche, W A, Gellibolian, R, Kang, S, Shimizu, M, Bowater, R P, Sinden, R R, Wells, R D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC40562/
https://ncbi.nlm.nih.gov/pubmed/7479928
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