Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.

Long CTG triplet repeats which are associated with several human hereditary neuromuscular disease genes are stabilized in ColE1-derived plasmids in Escherichia coli containing mutations in the methyl-directed mismatch repair genes (mutS, mutL, or mutH). When plasmids containing (CTG)180 were grown f...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Jaworski, A, Rosche, W A, Gellibolian, R, Kang, S, Shimizu, M, Bowater, R P, Sinden, R R, Wells, R D
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1995
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.11019
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