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Protein Conservation and Variation Suggest Mechanisms of Cell Type-Specific Modulation of Signaling Pathways

Many proteins and signaling pathways are present in most cell types and tissues and yet perform specialized functions. To elucidate mechanisms by which these ubiquitous pathways are modulated, we overlaid information about cross-cell line protein abundance and variability, and evolutionary conservat...

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Detalhes bibliográficos
Main Authors: Schaefer, Martin H., Yang, Jae-Seong, Serrano, Luis, Kiel, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055412/
https://ncbi.nlm.nih.gov/pubmed/24922536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003659
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