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Cell type-specific properties and environment shape tissue specificity of cancer genes

One of the biggest mysteries in cancer research remains why mutations in certain genes cause cancer only at specific sites in the human body. The poor correlation between the expression level of a cancer gene and the tissues in which it causes malignant transformations raises the question of which f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schaefer, Martin H., Serrano, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746590/
https://ncbi.nlm.nih.gov/pubmed/26856619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20707
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