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Modulation of human JAK-STAT pathway signaling by functionally conserved regulators

Both the core JAK-STAT pathway components and their in vivo roles have been widely conserved between vertebrates and invertebrate models such as Drosophila melanogaster. Misregulation of JAK-STAT pathway activity has also been identified as a key factor in the development of multiple human malignanc...

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Detalhes bibliográficos
Main Authors: Müller, Patrick, Pugazhendhi, Dhamayanthi, Zeidler, Martin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670133/
https://ncbi.nlm.nih.gov/pubmed/24058749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.18006
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