Ethanol self-administration and nicotine treatment increase brain levels of CYP2D in African green monkeys

BACKGROUND AND PURPOSE: CYP2D6 metabolizes many centrally acting drugs, neurotoxins and endogenous neurochemicals, and differences in brain levels of CYP2D have been associated with brain function and drug response. Alcohol consumers and smokers have higher levels of CYP2D6 in brain, but not liver,...

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Hlavní autoři: Miller, R T, Miksys, S, Hoffmann, E, Tyndale, R F
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055207/
https://ncbi.nlm.nih.gov/pubmed/24611668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12652
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