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Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
Cytochrome P450 (CYP) 2D6, an enzyme found in the liver and the brain, is involved in the metabolism of numerous centrally acting drugs (e.g. antidepressants, neuroleptics, opiates), endogenous neurochemicals (e.g. catecholamines) and in the inactivation of neurotoxins (e.g. pesticides, 1-methyl-4-p...
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| Published in: | Neuropharmacology |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5262474/ https://ncbi.nlm.nih.gov/pubmed/18687346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.07.017 |
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