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Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment

Cytochrome P450 (CYP) 2D6, an enzyme found in the liver and the brain, is involved in the metabolism of numerous centrally acting drugs (e.g. antidepressants, neuroleptics, opiates), endogenous neurochemicals (e.g. catecholamines) and in the inactivation of neurotoxins (e.g. pesticides, 1-methyl-4-p...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Mann, Amandeep, Miksys, Sharon, Lee, Anna, Mash, Deborah C., Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262474/
https://ncbi.nlm.nih.gov/pubmed/18687346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.07.017
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